A US man has become the first person in the world to get a heart transplant from a genetically-modified pig, according to BBC news report.
David Bennett, 57, is doing well three days after the experimental seven-hour procedure in Baltimore, doctors say.
The transplant was considered the last hope of saving Mr Bennett’s life, though it is not yet clear what his long-term chances of survival are.
Doctors at the University of Maryland Medical Center were granted a special dispensation by the US medical regulator to carry out the procedure, on the basis that Mr Bennett would otherwise have died.
He had been deemed ineligible for a human transplant, a decision that is often taken by doctors when the patient is in very poor health.
For the medical team who carried out the transplant, it marks the culmination of years of research and could change lives around the world.